Frankfurt vs Liverpool Predictions: 22.09.2025 - Champions League Betting Tips

Frankfurt vs Liverpool

Arne Slot needs his Liverpool side to get out of their slump, and will hope to avoid a fifth straight defeat against Frankfurt on Wednesday. After losing to Man United at home on Sunday, this tie is a huge game for the Premier League champions. If you're looking for betting tips on this week's Champions League games, our tipster Nathan Joyes has his say on Wednesdays game in Germany.

Frankfurt to fight back

Frankfurt's games this season have been nothing short of chaotic.

Goals galore - at both ends of the pitch - it's sometimes difficult to know what Frankfurt side is going to turn up from one week to the next.

Of late, however, it has become a little more obvious after winning just one of their last five. Within those matches, they have suffered three defeats - conceding four against Union Berlin, five against Atletico Madrid and three more recently vs Bayern.

Yet at the other end of the pitch they stuck six past Monchengladbach in an emphatic 6-4 victory - and their result against Bayern was the first time this season they've failed to find the back of the net.

Last time out at home in the Champions League they beat Galatasaray 5-1. Goals are almost guaranteed.

Panic stations for Liverpool

Liverpool have lost four matches in a row. That's not a sentence you read often.

It's certainly a concerning period for Arne Slot who now heads to Germany for a crucial Champions League tie - and with not much time to address what happened at Anfield on Sunday evening.

Liverpool started the season strongly - but were noticeably struggling to keep clean sheets and were also relying on late goals to bail them out. Perhaps those factors were brushed to one side while they were winning, but clearly it hasn't been sustainable for them.

And without a win now since September against Southampton, Slot needs to win - no matter what the performance looks like.

But will he get one? It feels only a matter of time before their lethal front line clicks.

Frankfurt vs Liverpool H2H

Frankfurt and Liverpool have only met twice - and both of those matches came all the way back in 1972. Liverpool edged past the Germans 2-0 on aggregate, sending them to the final 16 in the UEFA Cup. How Slot would love a similar result 53 years on from their first and only win against Frankfurt.

Our Frankfurt vs Liverpool betting tip

With both sides conceding goals left, right and centre - but still showing enough at the other end of the pitch to be a threat - Nathan Joyes is once again following the goal trend in Frankfurt. Let's take a look at his Champions League best bet.

Goals guaranteed in Germany

Frankfurt (4/1 with Betano) have scored 12  goals but conceded 18 in their last five. It's quite frankly - pardon the pun - insane.

Liverpool (4/7 with Betfred), on the other hand, have scored five yet conceded eight. Both defences are struggling at present - and with fixtures coming thick and fast, there isn't much time to address what is going wrong.

But both teams will very much fancy their chances.

The hosts stuck five past Galatasaray. At home, confidence will be high - and they will want to be the fifth team to topple Liverpool in a row.

Yet the visitors will be looking at how Atletico Madrid dismantled the Germans and put six past them in the previous round.

Neither side will be overly cautious - especially the hosts - and that could once again open up a goal fest at the Deutsche Bank Park.

Checking the Champions League betting odds for this fixture, over 3.5 match goals at 10/11 is very inviting.

TIP: Over 3.5 match goals at 10/11 with BetMGM.

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