Real Madrid vs RB Leipzig Prediction | UEFA Champions League | 21/10

The encounter between Real Madrid and RB Leipzig is set to kick off at 20:00 on Wednesday, 21/10, at Estadio Santiago Bernabéu.

This UEFA Champions League fixture offers an intriguing clash of form and tactics, with both sides eager to make a statement at this stage of the season.

Read our full prediction below and get some of the best betting insights based on statistics.

Our Recommended Bet

Our analysts at Betting.co.uk have examined key metrics and modelled the most likely match outcomes based on both teams' recent performance data.

This includes historical trends, home and away statistics, and efficiency in front of goal.

Have a look at our recommended bet and key insights below.

Recommended Bet

BTTS - No

Why we predict BTTS - No

Our recommended bet is BTTS – No for the Real Madrid vs RB Leipzig clash.

We expect one of the sides to keep a clean sheet, given the defensive organization and limited attacking consistency. A low-scoring affair could be on the cards here.

Key Betting Insights

Real Madrid

• Scored 13 goals in their last 5 matches
• Scored at least 1 goal in 5 consecutive matches
• Won 4 of their last 5 matches

RB Leipzig

• Scored 13 goals in their last 5 matches
• Over 9.5 corners occurred in 4 of RB Leipzig's last 5 matches
• Won 3 of their last 5 matches

BTTS - No: 5/4

Stake £10.00 → Potential Return £22.50

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Match Result

1x2 Odds Comparison

Bookmaker	1	X	2	Over 2.5	Under 2.5
	3/10	9/2	15/2	1/5	11/4
	2/9	6/1	10/1	1/4	3/1
	1/4	11/2	15/2	1/5	13/5
	1/4	6/1	7/1	1/4	13/5

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Real Madrid Preview

Real Madrid is coming to the clash with RB Leipzig with the current statistics in the UEFA Champions League:

• Matches played: 2

• Wins: 2

• Draws: 0

• Losses: 0

• Goals Scored: 6 (Avg. 3)

• Goals Conceded: 4 (Avg. 2)

When having a broader look at Real Madrid's performance in all competitions this year, the statistics are as follows:

• Matches played: 66

• Wins: 46

• Draws: 5

• Losses: 15

• Goals Scored: 144 (Avg. 2.18)

• Goals Conceded: 76 (Avg. 1.15)

Team Statistics/Latest Results

Real Madrid

Goals Scored: 144

Goals Conceded: 76

Average Goals Scored: 2.18

Average Goals Conceded: 1.15

Wins: 46

Goal Difference: 68

Date	Game	Result
14/10	Roma 3 - 4 Real Madrid	W
10/10	Real Madrid 1 - 0 Villarreal	W
20/09	Atlético Madrid 2 - 1 Real Madrid	L
15/09	Elche CF 2 - 3 Real Madrid	W
12/09	Real Madrid 4 - 1 Rayo Vallecano	W

Real Madrid to win the match: 3/10

Stake £10.00 → Potential Return £13.00

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RB Leipzig Preview

On the other hand, RB Leipzig comes into this fixture with the following statistics in UEFA Champions League:

• Matches played: 2

• Wins: 1

• Draws: 0

• Losses: 1

• Goals Scored: 2 (Avg. 1)

• Goals Conceded: 4 (Avg. 2)

Across all competitions this season, the team boasts the following performance:

• Matches played: 46

• Wins: 28

• Draws: 5

• Losses: 13

• Goals Scored: 100 (Avg. 2.17)

• Goals Conceded: 62 (Avg. 1.35)

Team Statistics/Latest Results

RB Leipzig

Goals Scored: 100

Goals Conceded: 62

Average Goals Scored: 2.17

Average Goals Conceded: 1.35

Wins: 28

Goal Difference: 38

Date	Game	Result
17/10	Bayern München 6 - 1 RB Leipzig	L
13/10	RB Leipzig 1 - 0 PSV	W
10/10	RB Leipzig 6 - 0 Eintracht Frankfurt	W
20/09	Bayer Leverkusen 2 - 0 RB Leipzig	L
13/09	RB Leipzig 5 - 0 Hamburger SV	W

RB Leipzig to win the match: 15/2

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Statistical Insights for Real Madrid vs RB Leipzig

With at least one of the two sides yet to record a match in this competition, a like-for-like statistical comparison is not yet available for this fixture.

Recent form across all competitions still offers a useful reference point:

Key metrics

Team Form

Real Madrid

Europe - UEFA Champions League

Form	Last 5 Games	PPG
Overall	W W L W W	2.4
Home	W W W W W	3
Away	W L W L W	1.8

RB Leipzig

Europe - UEFA Champions League

Form	Last 5 Games	PPG
Overall	L W W L W	1.8
Home	W W W W W	3
Away	L L L L W	0.6

Favourite

Home Win

1/4

80%

Draw

11/2

15.87%

Away Win

15/2

12.05%

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Key Metrics

Here's a breakdown of the core match metrics that often define betting value: goals scored, goals conceded, corners, and cards.

Analysing these stats offers a sharper view of team tendencies and helps identify markets with consistent trends.

Key metrics

Goals Scored

Real Madrid

13

last 5 matches

RB Leipzig

13

last 5 matches

Performance Gap

Both teams scored the same number of goals in the last 5 matches.

Real Madrid and RB Leipzig goals scored count, last 5 matches

▲

Roma

4

Villarreal

1

Atlético Madrid

1

Elche CF

3

Rayo Vallecano

4

1

Bayern München

1

PSV

6

Eintracht Frankfurt

0

Bayer Leverkusen

5

Hamburger SV

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Key metrics

Goals Conceded

Real Madrid

8

last 5 matches

RB Leipzig

8

last 5 matches

Performance Gap

Both teams conceded the same number of goals in the last 5 matches.

Real Madrid and RB Leipzig goals conceded count, last 5 matches

▲

Roma

3

Villarreal

0

Atlético Madrid

2

Elche CF

2

Rayo Vallecano

1

6

Bayern München

0

PSV

0

Eintracht Frankfurt

2

Bayer Leverkusen

0

Hamburger SV

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Key metrics

Corners

Real Madrid

35

last 5 matches

RB Leipzig

25

last 5 matches

Performance Gap

Real Madrid received +40% more corners than RB Leipzig in the last 5 matches.

Real Madrid and RB Leipzig corners count, last 5 matches

▲

Roma

9

Villarreal

9

Atlético Madrid

1

Elche CF

5

Rayo Vallecano

11

3

Bayern München

6

PSV

3

Eintracht Frankfurt

6

Bayer Leverkusen

7

Hamburger SV

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Key metrics

Cards

Real Madrid

10

last 5 matches

RB Leipzig

6

last 5 matches

Performance Gap

Real Madrid received +67% more cards than RB Leipzig in the last 5 matches.

Real Madrid and RB Leipzig cards count, last 5 matches

▲

Roma

1

Villarreal

5

Atlético Madrid

2

Elche CF

2

Rayo Vallecano

0

0

Bayern München

1

PSV

1

Eintracht Frankfurt

3

Bayer Leverkusen

1

Hamburger SV

Dave Kuzio Content Manager

Dave is an established football tipster and NCTJ and NCE qualified journalist. He has over 23 years experience writing for sports websites including Teletext Sport, and providing betting tips for some of the biggest football betting sites. For his sins, he is a Barnsley FC supporter and gets to as many games as possible with his two sons.